 |
| A |
A: Stages
of P. malariae in thin blood smears. Fig. 1: Normal
red cell; Figs. 2-5: Young trophozoites (rings); Figs.
6-13: Trophozoites; Figs. 14-22: Schizonts; Fig. 23: Developing
gametocyte; Fig. 24: Macrogametocyte (female); Fig. 25: Microgametocyte (male).
 |
| A |
A: Thick blood smear stages
of P. malariae
 |
| A |
A:
Ring-form trophozoites of P. malariae. Fig. 1: Normal red
blood cell; Figs. 2-5: Developing ring-form trophozoites.
Ring-form
trophozoites have one (rarely two) chromatin dots and a cytoplasm ring that
tends to be thicker than P. falciparum. 'Bird's-eye' forms may
appear. There is no enlargement of infected RBCs.
 |  |
| A | B |
A:
Ring-form (lower right) and developing (upper left) trophozoites of
P. malariae in a thick blood smear.
B: "Birds-eye" trophozoite of P. malariae in a thin blood
smear.
 |
 |
| C | D |
C,
D:
Ring-form trophozoites of P. malariae in thin blood smears.
 |
| A |
A:
Developing trophozoites of P. malariae. Figs. 6-13:
Developing trophozoites of P. malariae. Fig. 9 is a
'basket-form' trophozoite; Figs 10 and 13 are 'band-form'
trophozoites
In developing
trophozoites of P. malariae, chromatin is rounded or streaky and the
cytoplasm is usually compact with no vacuole. Pigment may be coarse
and peripheral. As the trophozoites mature, the cytoplasm may elongate
across the host RBC, forming a 'band-form', or may be oval with a vacuole
forming a 'basket-form'. Chromatin is usually in a single mass, less
definite in outline. Pigment granules become larger and tend to have a
more peripheral arrangement.
 |
 |
| A | B |
A, B:
Trophozoites of P. malariae in thick blood smears.
In developing
trophozoites of P. malariae, chromatin is rounded or streaky and the
cytoplasm is usually compact with no vacuole. Pigment may be coarse
and peripheral. As the trophozoites mature, the cytoplasm may elongate
across the host RBC, forming a 'band-form', or may be oval with a vacuole
forming a 'basket-form'. Chromatin is usually in a single mass, less
definite in outline. Pigment granules become larger and tend to have a
more peripheral arrangement.
 |
 |
| A | B |
A, B:
Band-form trophozoites of P. malariae in thin blood smears.
 |
 |
| C | D |
C,
D: Band-form trophozoites of P. malariae in a thin blood
smear.
 |
| E |
E: Band-form trophozoite of
P. malariae in a thin blood smear.
In developing
trophozoites of P. malariae, chromatin is rounded or streaky and the
cytoplasm is usually compact with no vacuole. Pigment may be coarse
and peripheral. As the trophozoites mature, the cytoplasm may elongate
across the host RBC, forming a 'band-form', or may be oval with a vacuole
forming a 'basket-form'. Chromatin is usually in a single mass, less
definite in outline. Pigment granules become larger and tend to have a
more peripheral arrangement.
 |
 |
| A | B |
A,
B: Basket-form trophozoites of P. malariae in a thin blood
smear.
 |
| C |
C:
Basket-form trophozoite of P. malariae in a thin blood smear.
 |
| A |
A:
Gametocytes of P. malariae. Fig. 23: Developing
gametocyte; Fig. 24: Macrogametocyte (female); Fig. 25:
Microgametocyte (male).
Gametocytes of
P. malariae are compact and tend to fill the host RBC. There is
no enlargement of the infected RBC and sometimes there is a reduction in
size. The cytoplasm stains blue and the chromatin pink to red.
Abundant dark pigment may be scattered throughout the cytoplasm.
 |
 |
| A | B |
A,
B: Gametocytes of P. malariae in thick blood smears.
 |
 |
| C | D |
C,
D: Gametocytes of P. malariae in thin blood smears.
 |
 |
| E | F |
E, F: Developing
gametocytes of P. malariae in thin blood smears.
 |
| A |
A:
Schizonts of P. malariae. Figs 14-20: Developing
schizonts; Figs. 21-22: Mature schizonts.
Schizonts of P. malariae have 6-12 (usually 8-10)
merozoites, often arranged in a rosette or irregular cluster. Mature
schizonts nearly fill the normal-sized host RBC. Pigment is course and
often peripheral. Schizonts can be common in peripheral blood
circulation.
 |
 |
| A | B |
A,
B: Schizonts of P. malariae in thick blood smears.
 |
 |
| C | D |
C,
D: Schizonts of P. malariae in thick blood smears.
Schizonts of P. malariae have 6-12 (usually 8-10)
merozoites, often arranged in a rosette or irregular cluster. Mature
schizonts nearly fill the normal-sized host RBC. Pigment if course and
often peripheral. Schizonts can be common in peripheral blood
circulation.
 |
 |
| A | B |
A, B:
Schizonts of P. malariae in thin blood smears.
 |
 |
| C | D |
C,
D:
Schizonts of P. malariae in a thin blood smear.
 |
 |
| E | F |
E, F:
Schizonts of P. malariae in thin blood smears.
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