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Stages
of P. ovale in thin blood smears. Fig. 1: Normal
red cell; Figs. 2-5: Young trophozoites (Rings); Figs.
6-15: Trophozoites; Figs. 16-23: Schizonts; Fig. 24:
Macrogametocytes (female); Fig. 25: Microgametocyte (male)
|
A:
|
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| A: Developing ring-form trophozoites of P. ovale. Fig. 1: Normal red blood cell; Figs. 2-5: Developing ring-form trophozoites. |
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| A: Schizonts of P. ovale. Figs. 16-22: Developing schizonts. Fig. 23: Mature schizont |
A
.
ing-form
trophozoites usually contain a single chromatin dot, but may contain double-chromatin
dots. Multiply-infected RBCs may be seen, making the rings difficult
to differentiate from P. falciparum. The single rings
may be difficult to differentiate from P. vivax, as the cytoplasm is
usually thick with a large chromatin dot. As the trophozoites mature,
they are less amoeboid than P. vivax and may exhibit fimbriation and
Schüffner's dots. Infected RBCs
are not usually enlarged as in P. vivax infections.
 |
 |
| A | B |
A, B:
Ring-form trophozoites of P. ovale in thick blood smears.
Ring-form
trophozoites usually contain a single chromatin dot, but may contain double-chromatin
dots. Multiply-infected RBCs may be seen, making the rings difficult
to differentiate from P. falciparum. The single rings
may be difficult to differentiate from P. vivax, as the cytoplasm is
usually thick with a large chromatin dot. As the trophozoites mature,
they are less amoeboid than P. vivax and may exhibit fimbriation and
Schüffner's dots. Infected RBCs
are not usually enlarged as in P. vivax infections.
 |
 |
| A | B |
A, B:
Ring-form trophozoites of P. ovale in thin blood smears. Note
the multiply-infected RBC in Figure A.
 |
| C |
C:
Ring-form trophozoites of P. ovale in a thin blood smear. Note
the multiply-infected RBC.
Developing
trophozoites of P. ovale are compact with little vacuolation.
Infected RBCs are often slightly enlarged and may exhibit fimbriation and
Schüffner's dots. Pigment is
less-coarse and diffuse.
 |
| A |
A:
Trophozoite of P. ovale in a thick blood smear.
Developing
trophozoites of P. ovale are compact with little vacuolation.
Infected RBCs are often slightly enlarged and may exhibit fimbriation and
Schüffner's dots. Pigment is
less-coarse and diffuse.
 |
 |
| A | B |
A: Trophozoite
of P. ovale in a thin blood smear. Note the fimbriation.
B: Trophozoite of P. ovale in a thin blood smear. Note the fimbriation and Schüffner's dots.
B: Trophozoite of P. ovale in a thin blood smear. Note the fimbriation and Schüffner's dots.
 |
 |
| C | D |
C:
Trophozoite of P. ovale in a thin blood smear. Note the
fimbriation and Schüffner's dots.
D: Trophozoites of P. ovale in a thin blood smear.
D: Trophozoites of P. ovale in a thin blood smear.
 |
 |
| E | F |
E: Infected RBCs showing
developing (lower) and ring-form (upper two) trophozoites of P. ovale
in a thin blood smear.
F: Trophozoites of P. ovale in a thin blood smear.
Gametocytes of P. ovale can be difficult to distinguish from those of
P. vivax, although there is generally less enlargement of the
infected RBC. The mature macrogametocyte fills the host RBC; the
microgametocyte is smaller. Schüffner's
dots may be seen with proper staining and fimbriation may occur.
 |
 |
| A | B |
A: Gametocyte
of P ovale in a thick blood smear.
B: Gametocyte of P. ovale (red arrow) nestled between two white blood cells in a thick blood smear.
B: Gametocyte of P. ovale (red arrow) nestled between two white blood cells in a thick blood smear.
Gametocytes of P. ovale can be difficult to distinguish from those of
P. vivax, although there is generally less enlargement of the
infected RBC. The mature macrogametocyte fills the host RBC; the
microgametocyte is smaller. Schüffner's
dots may be seen with proper staining and fimbriation may occur.
 |
 |
| A | B |
A:
Microgametocyte of P. ovale in a thin blood smear. Note the
elongated, oval shape and the Schüffner's
dots.
B: Macrogametocyte of P. ovale in a thin blood smear. Note the fimbriation.
B: Macrogametocyte of P. ovale in a thin blood smear. Note the fimbriation.
 |
 |
| C | D |
C:
Macrogametocyte of P. ovale in a thin blood smear. Note the
fimbriation.
D: Macrogametocyte of P. ovale in a thin blood smear, showing Schüffner's dots.
D: Macrogametocyte of P. ovale in a thin blood smear, showing Schüffner's dots.
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| E | F |
E, F:
Macrogametocytes of P. ovale in thin blood smears.
 |
| A |
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